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Calcium alternans produced by increased sarcoplasmic reticulum refractoriness

Autor
Rodriguez Cantalapiedra, I.; Lugo, C.A.; Peñaranda, A.; Echebarria, B.
Tipus d'activitat
Article en revista
Revista
Computers in Cardiology
Data de publicació
2011-09-29
Volum
38
Pàgina inicial
645
Pàgina final
648
Repositori
http://hdl.handle.net/2117/116131 Obrir en finestra nova
URL
http://www.cinc.org/archives/2011/pdf/0645.pdf Obrir en finestra nova
Resum
Despite the important role of electro-mechanical alternans in cardiac arrhythmogenesis, its molecular origin is not well understood. In this paper we want to study alternans that can be associated with alternations in the cytosolic calcium transient. To this end we study particularly, how a malfunction of Ryanodine Receptor (RyR) recovery time from in activation may induce beat-to-beat alternations in intracellular calcium concentration and how this could affect the stimulus propagation in inho...
Citació
Rodriguez Cantalapiedra, I., Lugo, C.A., Peñaranda, A., Echebarria, B. Calcium alternans produced by increased sarcoplasmic reticulum refractoriness. "Computers in Cardiology", 29 Setembre 2011, vol. 38, p. 645-648.
Paraules clau
Alternans Ryanodine Receptor
Grup de recerca
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
GICITED - Grup Interdiciplinari de Ciència i Tecnologia en l'Edificació

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