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PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation

Autor
Navarro, C.; Weaver, J.; Clark, A.; Clift, D.; Perez, S.; Castaño, Ó.; Zhou, D.; García, A.; Engel, E.
Tipus d'activitat
Article en revista
Revista
Acta biomaterialia
Data de publicació
2018-02
Volum
67
Pàgina inicial
53
Pàgina final
65
DOI
https://doi.org/10.1016/j.actbio.2017.12.009 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/114759 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S1742706117307651 Obrir en finestra nova
Resum
The use of human mesenchymal stromal cells (hMSC) for treating diseased tissues with poor vascularization has received significant attention, but low cell survival has hampered its translation to the clinic. Bioglasses and glass-ceramics have also been suggested as therapeutic agents for stimulating angiogenesis in soft tissues, but these effects need further evaluation in vivo. In this study, calcium-releasing particles and hMSC were combined within a hydrogel to examine their vasculogenic pote...
Citació
Navarro, C., Weaver, J., Clark, A., Clift, D., Perez, S., Castaño, Ó., Zhou, D., García, A., Engel, E. PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation. "Acta biomaterialia", Febrer 2018, vol. 67, p. 53-65.
Paraules clau
Calcium, Glass-ceramic particles, HMSC, Hydrogel, Vascularization
Grup de recerca
CREB - Centre de Recerca en Enginyeria Biomedica
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants

  • Navarro Requena, Claudia  (autor)
  • Weaver, Jessica D.  (autor)
  • Clark, Amy Y.  (autor)
  • Clift, Douglas  (autor)
  • Perez Amodio, Soledad Graciela  (autor)
  • Castaño Linares, Óscar  (autor)
  • Zhou, Dennis W.  (autor)
  • García, Andrés J.  (autor)
  • Engel Lopez, Elisabet  (autor)