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MicroRNAs expression, chromosomal alterations and immunoglobulin variable Heavy chain hypermutations in Mantle Cell Lymphomas

Autor
Navarro, A.; Beà, S.; Fernández, V.; Prieto, M.; Salaverria, I.; Jares, P.; Hartmann, E.; Mozos, A.; López-Guillermo, A.; Villamor, N.; Colomer, D.; Puig, X.; Ott, G.; Solé, F.; Serrano, S.; Rossenwald, A.; Campo, E.; Hernández, L.
Tipus d'activitat
Article en revista
Revista
Cancer research
Data de publicació
2009
Volum
69
Número
17
Pàgina inicial
7071
Pàgina final
7078
Repositori
http://hdl.handle.net/2117/6957 Obrir en finestra nova
URL
http://cancerres.aacrjournals.org/cgi/reprint/69/17/7071.pdf Obrir en finestra nova
Resum
The contribution of microRNAs (miR) to the pathogenesis of mantle cell lymphoma (MCL) is not well known.We investigated the expression of 86 mature miRs mapped to frequently altered genomic regions in MCL in CD5+/CD5 normal B cells, reactive lymph nodes, and purified tumor cells of 17 leukemic MCL, 12 nodal MCL, and 8MCL cell lines. Genomic alterations of the tumors were studied by single nucleotide polymorphism arrays and comparative genomic hybridization. Leukemic and nodal tumors showed a h...
Citació
Navarro, A. [et al.]. MicroRNAs expression, chromosomal alterations and immunoglobulin variable Heavy chain hypermutations in Mantle Cell Lymphomas. "Cancer research", 2009, vol. 69, núm. 17, p. 7071-7078.
Grup de recerca
ADBD - Anàlisi de Dades Complexes per a les Decisions Empresarials

Participants

  • Navarro, Alba  (autor)
  • Beà Bobet, Sílvia Margarit  (autor)
  • Fernández, Verónica  (autor)
  • Prieto, Miriam  (autor)
  • Salaverria, Itziar  (autor)
  • Jares, Pedro  (autor)
  • Hartmann, Elena  (autor)
  • Mozos, Anna  (autor)
  • López-Guillermo, A  (autor)
  • Villamor, Neus  (autor)
  • Colomer Pujol, Dolors  (autor)
  • Puig Oriol, Xavier  (autor)
  • Ott, German  (autor)
  • Solé, F  (autor)
  • Serrano, S  (autor)
  • Rossenwald, A  (autor)
  • Campo, E  (autor)
  • Hernández Calvento, Luis  (autor)

Arxius