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Influence of the surrounding environment in re-naturalized ß-barrel membrane proteins

Autor
Lopes, M.; Triguero, J.; Torras, J.; Perpète, Eric A.; Michaux, Catherine Anne Gisèle; Aleman, C.; Zanuy, D.
Tipus d'activitat
Article en revista
Revista
Biophysical chemistry
Data de publicació
2018-03-01
Volum
234
Pàgina inicial
6
Pàgina final
6
DOI
https://doi.org/10.1016/j.bpc.2017.12.003 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/113906 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0301462217304593?via%3Dihub Obrir en finestra nova
Resum
© 2017 Elsevier B.V. Outer-membrane porins are currently being used to prepare bioinspired nanomembranes for selective ion transport by immobilizing them into polymeric matrices. However, the fabrication of these protein-integrated devices has been found to be strongly influenced by the instability of the ß-barrel porin structure, which depends on surrounding environment. In this work, molecular dynamics simulations have been used to investigate the structural stability of a representative por...
Citació
Lopes, M., Triguero, J., Torras, J., Perpète, Eric A., Michaux, Catherine Anne Gisèle, Aleman, C., Zanuy, D. Influence of the surrounding environment in re-naturalized ß-barrel membrane proteins. "Biophysical chemistry", 1 Març 2018, vol. 234, p. 6.
Paraules clau
Bioinspired membrane, Detergent bilayer, Lipid bilayer, Membrane protein, Molecular dynamics
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants