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Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue

Autor
Hawks, C.; Elorza, J.; Echebarria, B.; Rodriguez Cantalapiedra, I.; Peñaranda, A.; Bragard, J.
Tipus d'activitat
Article en revista
Revista
Computing in Cardiology
Data de publicació
2016-01-01
Volum
42
Pàgina inicial
437
Pàgina final
440
Repositori
http://hdl.handle.net/2117/113755 Obrir en finestra nova
URL
http://www.cinc.org/archives/2015/pdf/0437.pdf Obrir en finestra nova
Resum
Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of the connexin family (Cx40; Cx43; Cx45 are the most common in human). These GJ modify the conductances between cardiac cell through a dynamical process. The aim of this study is to develop a bidomain model of the cardiac tis- sue where the dynamics of the connexins is also included. In...
Citació
Hawks, C., Elorza, J., Echebarria, B., Rodriguez Cantalapiedra, I., Peñaranda, A., Bragard, J. Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue. A: "Computers in Cardiology". 2016, p. 437-440.
Paraules clau
Cardiac Tissue, Gap junction dynamics, Reentrant Waves
Grup de recerca
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
GICITED - Grup Interdiciplinari de Ciència i Tecnologia en l'Edificació

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