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Computational detection of transcription factor binding sites through differential Rényi entropy

Autor
Maynou, J.; Gallardo, J.; Vallverdu, M.; Caminal, P.; Perera, A.
Tipus d'activitat
Article en revista
Revista
IEEE transactions on information theory
Data de publicació
2010-02-15
Volum
52
Número
2
Pàgina inicial
734
Pàgina final
741
DOI
https://doi.org/10.1109/TIT.2009.2037038 Obrir en finestra nova
URL
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5420289&tag=1 Obrir en finestra nova
Resum
Regulatory sequence detection is a critical facet for understanding the cell mechanisms in order to coordinate the response to stimuli. Protein synthesis involves the binding of a transcription factor to specific sequences in a process related to the gene expression initiation. A characteristic of this binding process is that the same factor binds with different sequences placed along all genome. Thus, any computational approach shows many difficulties related with this variability observed from...
Paraules clau
Binding Sites, Gene Regulation, Motif Detection, Rényi Entropy, Sequence Analysis, Transcription Factor
Grup de recerca
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Centre de Recerca en Enginyeria Biomedica

Participants