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Different assembly of type IV collagen on hydrophilic and hydrophobic substrata alters endothelial cells interaction

Autor
Coelho, N.M.; Gonzalez, C.; Planell, J. A.; Salmeron, M.; Altankov, G.
Tipus d'activitat
Article en revista
Revista
European cells and materials
Data de publicació
2010-06
Volum
19
Pàgina inicial
262
Pàgina final
272
Repositori
http://hdl.handle.net/2117/8475 Obrir en finestra nova
URL
http://www.ecmjournal.org/journal/papers/vol019/pdf/v019a25.pdf Obrir en finestra nova
Resum
Considering the structural role of type IV collagen (Col IV) in the assembly of the basement membrane (BM) and the perspective of mimicking its organization for vascular tissue engineering purposes, we studied the adsorption pattern of this protein on model hydrophilic (clean glass) and hydrophobic trichloro(octadecyl)silane (ODS) surfaces known to strongly affect the behavior of other matrix proteins. The amount of fluorescently labeled Col IV was quantified showing saturation of the surface fo...
Citació
Coelho, N. [et al.]. Different assembly of type IV collagen on hydrophilic and hydrophobic substrata alters endothelial cells interaction. "European cells and materials", Juny 2010, vol. 19, p. 262-272.
Grup de recerca
CREB - Centre de Recerca en Enginyeria Biomedica
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants

  • Coelho, Nuno Miranda Guerra  (autor)
  • Gonzalez Garcia, C.  (autor)
  • Planell Estany, Josep Antón  (autor)
  • Salmeron Sánchez, M  (autor)
  • Altankov, George Petrov  (autor)