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Perfusion cell seeding on large porous PLA/calcium phosphate composite scaffolds in a perfusion bioreactor system under varying perfusion parameters

Autor
Koch, M.A.; Vrij, E.; Engel, E.; Planell, J. A.; Lacroix, D.
Tipus d'activitat
Article en revista
Revista
Journal of biomedical materials research. Part A
Data de publicació
2010-12-15
Volum
95A
Número
4
Pàgina inicial
1011
Pàgina final
1018
DOI
https://doi.org/10.1002/jbm.a.32927 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/14595 Obrir en finestra nova
URL
http://cataleg.upc.edu/record=b1381027~S1*cat Obrir en finestra nova
Resum
A promising approach to bone tissue engineering lies in the use of perfusion bioreactors where cells are seeded and cultured on scaffolds under conditions of enhanced nutrient supply and removal of metabolic products. Fluid flow alterations can stimulate cell activity, making the engineering of tissue more efficient. Most bioreactor systems are used to culture cells on thin scaffold discs. In clinical use, however, bone substitutes of large dimensions are needed. In this study, MG63 osteoblast-l...
Citació
Koch, M. [et al.]. Perfusion cell seeding on large porous PLA/calcium phosphate composite scaffolds in a perfusion bioreactor system under varying perfusion parameters.. "Journal of biomedical materials research. Part A", 17 Desembre 2010, vol. 95, núm. 4, p. 1011-1018.
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants