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Detection, properties, and frequency of local calcium release from the sarcoplasmic reticulum in teleost cardiomyocytes

Autor
Llach, A.; Molina, C.; Alvarez-Lacalle, E.; Tort, L.; Hove-Madsen, L.; Benitez, R.
Tipus d'activitat
Article en revista
Revista
PLoS one
Data de publicació
2011-08-29
Volum
6
Número
8
Pàgina inicial
e23708
DOI
https://doi.org/10.1371/journal.pone.0023708 Obrir en finestra nova
Projecte finançador
Aplicación de técnicas de análisis de sistemas complejos al estudio de problemas de fisiología cardíaca.
Repositori
http://hdl.handle.net/2117/13714 Obrir en finestra nova
URL
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0023708 Obrir en finestra nova
Resum
Calcium release from the sarcoplasmic reticulum (SR) plays a central role in the regulation of cardiac contraction and rhythm in mammals and humans but its role is controversial in teleosts. Since the zebrafish is an emerging model for studies of cardiovascular function and regeneration we here sought to determine if basic features of SR calcium release are phylogenetically conserved. Confocal calcium imaging was used to detect spontaneous calcium release (calcium sparks and waves) from the SR. ...
Citació
Llech, A. [et al.]. Detection, properties, and frequency of local calcium release from the sarcoplasmic reticulum in teleost cardiomyocytes. "PLoS ONE Journal Information", 29 Agost 2011, vol. 6, núm. 8.
Grup de recerca
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
CREB - Centre de Recerca en Enginyeria Biomedica

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