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Surface characterization and cell response of a PLA/CaP glass biodegradable composite material

Autor
Navarro Bernal, Manuel; Engel, E.; Planell, J. A.; Amaral, I.; Barbosa, M.; Ginebra, M.P.
Tipus d'activitat
Article en revista
Revista
Journal of biomedical materials research. Part B, Applied biomaterials
Data de publicació
2008-05
Volum
85A
Número
2
Pàgina inicial
477
Pàgina final
486
DOI
https://doi.org/10.1002/jbm.a.31546 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.31546/abstract Obrir en finestra nova
Resum
Bioabsorbable materials are of great interest for bone regeneration applications, since they are able to degrade gradually as new tissue is formed. In this work, a fully biodegradable composite material containing polylactic acid (PLA) and calcium phosphate (CaP) soluble glass particles has been characterized in terms of surface properties and cell response. Cell cultures were performed in direct contact with the materials and also with their extracts, and were evaluated using the MTT assay, alk...
Paraules clau
cell culture, glass, in vitro test, polylactic acid, surface analysis
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants