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Individual-based model and simulation of Plasmodium falciparum infected erythrocyte in vitro cultures

Autor
Ferrer, J.; Vidal, J.; Prats, C.; Valls, J.; Herreros, E.; Lopez, D.; Giro, A.; Gargallo, D.
Tipus d'activitat
Article en revista
Revista
Journal of theoretical biology
Data de publicació
2007-10
Volum
248
Número
3
Pàgina inicial
448
Pàgina final
459
Repositori
http://hdl.handle.net/2117/10584 Obrir en finestra nova
Resum
Malaria is still one of the most fatal diseases in the world. Development of an effective treatment or vaccine requires the cultivation of the parasite that causes it: Plasmodium falciparum. Several methods for in vitro cultivation of P. falciparum infected erythrocytes have been successfully developed and described in the last 30 years. Some problems arising from the current harvests are the low parasitaemia and daily human supervision requirements. The lack of a suitable model for global cultu...
Citació
Ferrer, J. [et al.]. Individual-based model and simulation of Plasmodium falciparum infected erythrocyte in vitro cultures. "Journal of theoretical biology", Octubre 2007, vol. 248, núm. 3, p. 448-459.
Paraules clau
Individual-based Model Plasmodium Falciparum Simulation Merozoite Erythrocyte In Vitro Culture Malaria
Grup de recerca
SC-SIMBIO - Sistemes complexos. Simulació discreta de materials i de sistemes biològics

Participants