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Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of mycobacterium tuberculosis

Autor
Cáceres, N.; Llopis, I.; Marzo, E.; Prats, C.; Vilaplana, C.; García de Viedma, D.; Samper, S.; Lopez, D.; Cardona, P.J.
Tipus d'activitat
Article en revista
Revista
PloS one
Data de publicació
2012-01-03
Volum
7
Número
1
Pàgina inicial
e29010
DOI
https://doi.org/10.1371/journal.pone.0029010 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/16232 Obrir en finestra nova
Resum
Background: Evaluation of a quick and easy model to determine the intrinsic ability of clinical strains to generate active TB has been set by assuming that this is linked to the fitness of Mycobacterium tuberculosis strain at the innate phase of the infection. Thus, the higher the bacillary load, the greater the possibility of inducting liquefaction, and thus active TB, once the adaptive response is set. Methodology/Principal Findings: The virulence of seven clinical Mycobacterium tuberculosis s...
Citació
Cáceres, N. [et al.]. Low dose aerosol fitness at the innate phase of murine infection better predicts virulence amongst clinical strains of mycobacterium tuberculosis. "PLoS One", 03 Gener 2012, vol. 7, núm. 1.
Grup de recerca
SC-SIMBIO - Sistemes complexos. Simulació discreta de materials i de sistemes biològics

Participants

  • Cáceres, Neus  (autor)
  • Llopis Fuste, Isaac  (autor)
  • Marzo, Elena  (autor)
  • Prats Soler, Clara  (autor)
  • Vilaplana, Cristina  (autor)
  • García de Viedma, Darío  (autor)
  • Samper, Sofia  (autor)
  • Lopez Codina, Daniel  (autor)
  • Cardona Iglesias, Pere Joan  (autor)

Arxius