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Synaptic depression and slow oscillatory activity in a biophysical network model of the cerebral cortex

Autor
Benita, J.; Guillamon, A.; Deco, G.; Sánchez-Vives, M.
Tipus d'activitat
Article en revista
Revista
Frontiers in computational neuroscience
Data de publicació
2012-08-28
Volum
6
Número
64
Pàgina inicial
1
Pàgina final
17
DOI
https://doi.org/10.3389/fncom.2012.00064 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/16721 Obrir en finestra nova
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428579/ Obrir en finestra nova
Resum
Short-termsynapticdepression(STD)isaformofsynapticplasticitythathasalargeimpactonnetworkcomputations.ExperimentalresultssuggestthatSTDismodulatedbycorticalactivity,decreasingwithactivityinthenetworkandincreasingduringsilentstates.Here,weexploreddifferentactivity-modulationprotocolsinabiophysicalnetworkmodelforwhichthemodeldisplayedlessSTDwhenthenetworkwasactivethanwhenitwassilent,inagreementwithexperimentalresults.Furthermore,westudiedhowtrainsofsynapticpotentialshadlesserdecayduringperiodsofact...
Citació
Benita, J. [et al.]. Synaptic depression and slow oscillatory activity in a biophysical network model of the cerebral cortex. "Frontiers in Computational Neuroscience", 28 Agost 2012, vol. 6, núm. 64, p. 1-17.
Paraules clau
cortical activity, network model, short-term depression, synaptic plasticity, up/down state
Grup de recerca
SD - Sistemes Dinàmics de la UPC

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