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GenNon-h: Generating multiple sequence alignments on nonhomogeneous phylogenetic trees

Author
Kedzierska, A.; Casanellas, M.
Type of activity
Journal article
Journal
BMC bioinformatics
Date of publication
2012-08-28
Volume
13
Number
216
First page
1
Last page
4
DOI
https://doi.org/10.1186/1471-2105-13-216 Open in new window
Project funding
Geometría de variedades algebraicas y aplicaciones
Repository
http://hdl.handle.net/2117/17957 Open in new window
URL
http://www.biomedcentral.com/1471-2105/13/216/abstract Open in new window
Abstract
Background: A number of software packages are available to generate DNA multiple sequence alignments (MSAs) evolved under continuous-time Markov processes on phylogenetic trees. On the other hand, methods of simulating the DNA MSA directly from the transition matrices do not exist. Moreover, existing software restricts to the time-reversible models and it is not optimized to generate nonhomogeneous data (i.e. placing distinct substitution rates at different lineages). Results: We present the fir...
Citation
Kedzierska, A.; Casanellas, M. GenNon-h: Generating multiple sequence alignments on nonhomogeneous phylogenetic trees. "BMC bioinformatics", 28 Agost 2012, vol. 13, núm. 216, p. 1-4.
Group of research
GEOMVAP - Geometry of Manifolds and Applications

Participants

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