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High rate of reversibility of renal damage in a cohort of HIV-infected patients receiving tenofovir-containing antiretroviral therapy

Author
Bonjoch, A.; Echeverria, P.; Perez, N.; Puig, J.; Estany, C.; Clotet, B.; Negredo, E.
Type of activity
Journal article
Journal
Antiviral research
Date of publication
2012-10
Volume
96
Number
1
First page
65
Last page
69
DOI
https://doi.org/10.1016/j.antiviral.2012.07.009 Open in new window
Abstract
We assessed the progress of renal damage after discontinuation of tenofovir (TDF) in patients who started therapy with normal renal parameters. Normal local reference values were as follows: estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease equation (MDRD), ¿60 mL/min/1.73 m2; creatinine, ¿1.20 mg/dL; serum phosphate: ¿2.69 mg/dL; proteinuria: <30 mg/dL, and glycosuria: <20 mg/dL in nondiabetic patients. A logistic regression analysis was used to eval...
Keywords
HIV, Renal impairment, Reversibility, Tenofovir, Toxicity
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Bonjoch Badia, Anna  (author)
  • Echeverria Liras, Patricia  (author)
  • Perez Alvarez, Nuria  (author)
  • Puig Domingo, Jordi  (author)
  • Estany Quera, Carla  (author)
  • Clotet Sala, Bonaventura  (author)
  • Negredo Puigmal, Eugènia  (author)