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Network-based enrichment analysis of gene expression through protein-protein interaction data

Autor
Massanet, R.; Fernandez, F.; Perera, A.; Caminal, P.
Tipus d'activitat
Presentació treball a congrés
Nom de l'edició
34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Any de l'edició
2012
Data de presentació
2012-09-01
Llibre d'actes
Annual international conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2012 : San Diego, California, USA, Aug. 28-1Sept. 1, 2012
Pàgina inicial
6317
Pàgina final
6320
Editor
IEEE
DOI
https://doi.org/10.1109/EMBC.2012.6347438 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/17221 Obrir en finestra nova
Resum
High-throughput analysis of gene expression data is subject to technological and statistical issues that confuse the underlying expression-condition associations. In this contribution a network-based candidate gene prioritization strategy was applied to the enrichment of a publicly available gene expression dataset, focused on the study of the mechanosensitivity of genes exposed to altered pulmonary matrix stiffness. Results suggested that some genes which had not been taken into account in the ...
Citació
Massanet, R. [et al.]. Network-based enrichment analysis of gene expression through protein-protein interaction data. A: IEEE Engineering in Medicine and Biology Society. "34th Annual International Conference of the IEEE EMBS San Diego, California USA, 28 August-1 September, 2012". San Diego, California: IEEE, 2012, p. 6317-6320.
Grup de recerca
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Centre de Recerca en Enginyeria Biomedica

Participants