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Nonlinearities due to refractoriness in SR Ca release

Author
Peñaranda, A.; Alvarez-Lacalle, E.; Rodriguez Cantalapiedra, I.; Echebarria, B.
Type of activity
Journal article
Journal
Computing in Cardiology
Date of publication
2013-01-01
Volume
39
First page
297
Last page
300
Project funding
DINÁMICA NO LINEAL Y ESTOCÁSTICA EN SISTEMAS FÍSICOS Y BIOFÍSICOS
Grup recerca consolidat: Grup de Turbulencia, Fluctuacions i Difusio
MODELOS Y CATACTERIZACIÓN DE DINÁMICA CARDIACA
Repository
http://hdl.handle.net/2117/169413 Open in new window
URL
http://www.cinc.org/archives/2012/pdf/0297.pdf Open in new window
Abstract
Calcium alternans is a pro-arrhytmic cardiac dysfunction related to beat-to-beat changes in the amplitude of intracellular calcium transient, that typically occurs at rapid pacing rates. Although oscillations in sarcoplasmic reticulum (SR) content have been related with calcium alternans, the experimental appearance of alternans without these oscillations suggests that another mechanism related with refractoriness of SR calcium release might be key, at least, under certain conditions. We investi...
Citation
Peñaranda, A. [et al.]. Nonlinearities due to refractoriness in SR Ca release. A: "Computing in Cardiology". Institute of Electrical and Electronics Engineers (IEEE), 2013, p. 297-300.
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

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