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Cardiac dynamics: a simplified model for action potential propagation

Author
Peñaranda, A.; Rodriguez Cantalapiedra, I.; Bragard, J.; Echebarria, B.
Type of activity
Journal article
Journal
Theoretical biology and medical modeling
Date of publication
2012-11-29
Volume
9
First page
50
Last page
68
DOI
https://doi.org/10.1186/1742-4682-9-50 Open in new window
Project funding
FIS2011-28820
GRUP INTERDISCIPLINAR DE CIÈNCIA I TECNOLOGIA A L'EDIFICACIÓ (GICITED)
URL
http://www.tbiomed.com/content/9/1/50 Open in new window
Abstract
This paper analyzes a new semiphysiological ionic model, used recently to study reexitations and reentry in cardiac tissue [I.R. Cantalapiedra et al, PRE 82 011907 (2010)]. The aim of the model is to reproduce action potencial morphologies and restitution curves obtained, either from experimental data, or from more complex electrophysiological models. The model divides all ion currents into four groups according to their function, thus resulting into fast-slow and inward-outward currents. We sho...
Keywords
DEATH, DISPERSION, EXCITATION, HEART-FAILURE, HETEROGENEITY, ION CHANNELS, MECHANISMS, RESTITUTION, SIMULATION, TISSUE
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

Participants