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A model of large-scale proteome evolution

Author
Vicente, R.; Pastor-Satorras, R.; Smith, E.; Kepler, T.B.
Type of activity
Journal article
Journal
Advances in complex systems
Date of publication
2002-03
Volume
5
Number
1
First page
43
Last page
54
DOI
https://doi.org/10.1142/S021952590200047X Open in new window
Repository
http://hdl.handle.net/2117/126056 Open in new window
https://arxiv.org/abs/cond-mat/0207311 Open in new window
URL
https://www.worldscientific.com/doi/abs/10.1142/S021952590200047X Open in new window
Abstract
The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have shown that its topology displays a number of surprising features shared by other complex networks, both natural and artificial. In order to understand the origins of this topology and its evolutionary implications, we present a simple model of proteome evoluti...
Citation
Vicente, R., Pastor-Satorras, R., Smith, E., Kepler, T.B. A model of large-scale proteome evolution. "Advances in complex systems", Març 2002, vol. 5, núm. 1, p. 43-54.
Keywords
Gene duplication, Genomics, Networks, Proteomics, Small-world
Group of research
SC-SIMBIO - Complex systems. Computer simulation of materials and biological systems

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