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A model of large-scale proteome evolution

Autor
Vicente, R.; Pastor-Satorras, R.; Smith, E.; Kepler, T.B.
Tipus d'activitat
Article en revista
Revista
Advances in complex systems
Data de publicació
2002-03
Volum
5
Número
1
Pàgina inicial
43
Pàgina final
54
DOI
https://doi.org/10.1142/S021952590200047X Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/126056 Obrir en finestra nova
https://arxiv.org/abs/cond-mat/0207311 Obrir en finestra nova
URL
https://www.worldscientific.com/doi/abs/10.1142/S021952590200047X Obrir en finestra nova
Resum
The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have shown that its topology displays a number of surprising features shared by other complex networks, both natural and artificial. In order to understand the origins of this topology and its evolutionary implications, we present a simple model of proteome evoluti...
Citació
Vicente, R., Pastor-Satorras, R., Smith, E., Kepler, T.B. A model of large-scale proteome evolution. "Advances in complex systems", Març 2002, vol. 5, núm. 1, p. 43-54.
Paraules clau
Gene duplication, Genomics, Networks, Proteomics, Small-world
Grup de recerca
SC-SIMBIO - Sistemes complexos. Simulació discreta de materials i de sistemes biològics

Participants

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