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Incorporation of a clot-binding peptide into polythiophene: properties of composites for biomedical applications

Autor
Fabregat, G.; Teixeira-Dias, Bruno; del Valle, LJ.; Armelin, E.; Estrany, F.; Aleman, C.
Tipus d'activitat
Article en revista
Revista
ACS applied materials and interfaces
Data de publicació
2014-08-13
Volum
6
Número
15
Pàgina inicial
11940
Pàgina final
11954
DOI
https://doi.org/10.1021/am503904h Obrir en finestra nova
Projecte finançador
POLIMEROS CONDUCTORES Y SUS DERIVADOS HIBRIDOS CON APLICACIONES AVANZADAS
Repositori
http://hdl.handle.net/2117/24140 Obrir en finestra nova
URL
http://pubs.acs.org/doi/abs/10.1021/am503904h Obrir en finestra nova
Resum
Biocomposites formed by a pentapeptide (CREKA), which recognizes clotted plasma proteins, entrapped into the poly(3,4-ethylenedioxythiophene) (PEDOT) matrix have been prepared using three very different procedures. X-ray photoelectron spectroscopy analyses indicate that PEDOT-CREKA films, prepared by chronoamperometry in basic aqueous solution (pH = 10.3) and deposited onto a PEDOT internal layer, present the higher concentration of peptide: one CREKA molecule per six polymer repeat units. The s...
Citació
Fabregat, G. [et al.]. Incorporation of a clot-binding peptide into polythiophene: properties of composites for biomedical applications. "ACS applied materials and interfaces", 13 Agost 2014, vol. 6, núm. 15, p. 11940-11954.
Paraules clau
4-ETHYLENEDIOXYTHIOPHENE) FILMS, CELL ATTACHMENT, CONDUCTING POLYMER, ELECTROCHEMICAL SYNTHESIS, IN-VIVO, MULTILAYERED FILMS, NEURAL PROBES, POLY(3, POLYPYRROLE, RAY PHOTOELECTRON-SPECTROSCOPY, X-RAY, cell proliferation, composite, electroactive polymer, fibrin, peptide
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

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