Soft active tissues exhibit softening, hardening, and reversible fluidisation. The result of these non-linear behaviour is due to multiple processes taking part at
different scales: active protein motors that actuate at the polymeric structure of the cell, (de)polymerisation and remodelling of the cytoskeleton, and cell-cell connectivity changes that take place at the tissue level.
Asadipour, N.; Mosafa, P.; Muñoz, J. Cell-centred model for non-linear tissue rheology and active remodelling. A: World Congress on Computational Mechanics. "11th. World Congress on Computational Mechanics". Barcelona: Centre Internacional de Mètodes Numèrics en Enginyeria (CIMNE), 2014, p. 1-10.