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Classification models for neurocognitive impairment in HIV infection based on demographic and clinical variables

Author
Muñoz-Moreno, J.A.; Perez, N.; Muñoz, A.; Prats, A.; Garolera, M.; Jurado, M.; Fumaz, C.R.; Negredo, E.; Ferrer, M.; Clotet, B.
Type of activity
Journal article
Journal
PloS one
Date of publication
2014-09-19
Volume
9
Number
9
First page
e107625-1
Last page
e107625-7
DOI
https://doi.org/10.1371/journal.pone.0107625 Open in new window
Abstract
Objective: We used demographic and clinical data to design practical classification models for prediction of neurocognitive impairment (NCI) in people with HIV infection.; Methods: The study population comprised 331 HIV-infected patients with available demographic, clinical, and neurocognitive data collected using a comprehensive battery of neuropsychological tests. Classification and regression trees (CART) were developed to obtain detailed and reliable models to predict NCI. Following a practi...
Keywords
AGE, ANTIRETROVIRAL THERAPY, CD4 NADIR, CENTRAL-NERVOUS-SYSTEM, CEREBROSPINAL-FLUID, COGNITIVE RESERVE, DISORDERS, EDUCATION, INDIVIDUALS, PREDICTOR
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Muñoz Moreno, Jose Antonio  (author)
  • Perez Alvarez, Nuria  (author)
  • Muñoz Murillo, Amalia  (author)
  • Prats París, Anna  (author)
  • Garolera Freixa, Maite  (author)
  • Jurado Luque, Maria Àngels  (author)
  • Rodriguez Fumaz, Carmina  (author)
  • Negredo Puigmal, Eugènia  (author)
  • Ferrer Lasala, Maria Jose  (author)
  • Clotet Sala, Bonaventura  (author)