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Exploring Diallelic genetic markers: The Hardy Weinberg package

Author
Graffelman, J.
Type of activity
Journal article
Journal
Journal of statistical software
Date of publication
2015-03
Volume
64
Number
3
First page
1
Last page
23
Repository
http://hdl.handle.net/2117/76647 Open in new window
URL
http://www.jstatsoft.org/v64/i03 Open in new window
Abstract
Testing genetic markers for Hardy-Weinberg equilibrium is an important issue in genetic association studies. The HardyWeinberg package o ers the classical tests for equilibrium, functions for power computation and for the simulation of marker data under equilibrium and disequilibrium. Functions for testing equilibrium in the presence of missing data by using multiple imputation are provided. The package also supplies various graphical tools such as ternary plots with acceptance regions, log-rati...
Citation
Graffelman, J. Exploring Diallelic genetic markers: The Hardy Weinberg package. "Journal of statistical software", Març 2015, núm. 3, p. 1-23.
Keywords
Q-Q plot, chi-square test, exact test, log-ratio., permutation test, power, ternary plot
Group of research
COSDA-UPC - COmpositional and Spatial Data Analysis

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