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Ethanol induces hydroxytyrosol formation in humans

Author
Perez, C.; Farré, M.; Pujadas, M.; Mustata, C.; Menoyo, E.; Pastor, A.; Langohr, K.; De la Torre, R.
Type of activity
Journal article
Journal
Pharmacological research
Date of publication
2015
Volume
95-96
First page
27
Last page
33
DOI
https://doi.org/10.1016/j.phrs.2015.02.008 Open in new window
Repository
http://hdl.handle.net/2117/78494 Open in new window
URL
http://www.sciencedirect.com/science/article/pii/S1043661815000316 Open in new window
Abstract
Previous studies in animals have shown an increase of hydroxytyrosol (OHTyr), a potent phenolic antioxidant and a minor metabolite of dopamine (also called 3,4-dihydroxyphenylethanol or DOPET), after ethanol intake. The interaction between ethanol and dopamine metabolism is the probable mechanism involved. The aim of the study was to establish the contribution of the dose of ethanol on OHTyr formation. 24 healthy male volunteers were included. Subjects were distributed in three different cohorts...
Citation
Pérez-Mañá, C., Farré, M., Pujadas, M., Mustata, C., Menoyo, E., Pastor, A., Langohr, K., De la Torre, R. Ethanol induces hydroxytyrosol formation in humans. "Pharmacological research", 2015, vol. 95-96, p. 27-33.
Keywords
Alcohol, DOPET, Dopamine, Hydroxytyrosol, Tyrosol
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Perez Maña, Clara  (author)
  • Farré, Magí  (author)
  • Pujadas, Mitona  (author)
  • Mustata, Cristina  (author)
  • Menoyo, Ester  (author)
  • Pastor, Antoni  (author)
  • Langohr, Klaus  (author)
  • De la Torre Fornell, Rafael  (author)

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