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Novel mode of recognition by HMG proteins

Author
Sanchez-Giraldo,R; Acosta, F.J.; Saperas, N.; Millan, C.; Garcia, S.; Churchill, M.E.A.; Campos, J.Lourdes
Type of activity
Presentation of work at congresses
Name of edition
XXII Jornades de Biologia Molecular
Date of publication
2015
Presentation's date
2015-06
Book of congress proceedings
XXII Jornades de Biologia Molecular - Llibre de resums
First page
36
Last page
36
URL
http://scb.iec.cat/wp-content/uploads/2015/05/Programa-i-llibre-de-resums-XXII-JBM-2015.pdf Open in new window
Abstract
HMGB proteins are members of the High Mobility Group (HMG) proteins. They are architectural proteins that affect cellular functions by modulating chromatin structure and thereby gene expression in eukaryotic cells. HMGB1 is considered the archetypa l member of the HMGB family. It participates in the regulation of transcription, chromatin remodeling, recombination and DNA repair. In an extracellular role, HMGB1 is a danger signal in inflammatory conditions, including autoimmunity a...
Group of research
CEBIM - Molecular Biotechnology Centre
MACROM - Crystallography, Structure and Function of Biological Macromolecules

Participants