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A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

Author
de Sola, S.; De la Torre, R.; Gonzalo Sanchez-Benavides; Benejam, B.; Cuenca, A.; del Hoyo, L.; Rodríguez, J.; Catuara-Solarz, S.; Sánchez-Gutiérrez, J.; Dueñas-Espín, I.; Hernández, G.; Peña-Casanovas, J.; Langohr, K.; Videla, S.; Blehaut, H.; Farré, M.; Dierssen, M.
Type of activity
Journal article
Journal
Frontiers in Psychology
Date of publication
2015-06-04
Volume
6
First page
1
Last page
14
DOI
10.3389/fpsyg.2015.00708
Repository
http://hdl.handle.net/2117/78506 Open in new window
URL
http://journal.frontiersin.org/article/10.3389/fpsyg.2015.00708/full Open in new window
Abstract
The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological challenges and questioned the prevailing methodology used to evaluate cognitive functioning of DS individuals. This is usually achieved by comparing DS individuals to matched healthy controls of the same mental age. We propose a new tool, the TESDAD Battery that uses comparison wit...
Citation
de Sola, S., De la Torre, R., Sánchez Benavides, G., Benejam, B., Cuenca, A., del Hoyo, L., Rodríguez, J., Catuara-Solarz, S., Sánchez-Gutiérrez, J., Dueñas-Espín, I., Hernández, G., Peña-Casanovas, J., Langohr, K., Videla, S., Blehaut, H., Farré, M., Dierssen, M. A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials. "Frontiers in Psychology", 04 Juny 2015, vol. 6, p. 1-14.
Keywords
ALZHEIMERS-DISEASE, DYSFUNCTION, Down syndrome, EXECUTIVE FUNCTION, GENDER-DIFFERENCES, NONDEMENTED ADULTS, QUALITY-OF-LIFE, TESDAD neurocognitive battery, VOXEL-BASED MORPHOMETRY, WILLIAMS-SYNDROME, WORKING-MEMORY, YOUNG-ADULTS, clinical trials as topic, cognition, intellectual disabilities
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • de Sola Llopis, Susana  (author)
  • De la Torre Fornell, Rafael  (author)
  • Sánchez Benavides, Gonzalo  (author)
  • Benejam, Bessy  (author)
  • Cuenca, Aída  (author)
  • del Hoyo, Laura  (author)
  • Rodríguez, Joan  (author)
  • Catuara-Solarz, Silvina  (author)
  • Sánchez-Gutiérrez, Judit  (author)
  • Dueñas-Espín, Ivan  (author)
  • Hernández, Gimena  (author)
  • Peña Casanovas, Jordi  (author)
  • Langohr, Klaus  (author)
  • Videla, Sebastià  (author)
  • Blehaut, Henri  (author)
  • Farré, Magí  (author)
  • Dierssen, Mara  (author)

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