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A shared-parameter joint model for prostate cancer risk and psa longitudinal profiles

Author
Serrat, C.; Rué, M.; Perpiñán, H.; Forte, A.; Armero, C.; Piulachs, X.; Páez, Á.; Gómez Melis, Guadalupe
Type of activity
Presentation of work at congresses
Name of edition
2015 International Conference on Risk Analysis
Date of publication
2015
Presentation's date
2015-05-29
Book of congress proceedings
Current topics on risk analysis: ICRA 6 and RISK 2015 conference
First page
711
Last page
719
Publisher
Fundación Mapfre
Project funding
Grup de Recerca en Bioestadística i Bioinformàtica (GRBIO)
Métodos avanzados en estudios de seguimiento: diseño de ensayos clínicos, datos longitudinales y censura en un intervalo
Repository
http://hdl.handle.net/2117/82670 Open in new window
URL
http://www.mapfre.com/documentacion/publico/i18n/catalogo_imagenes/grupo.cmd?path=1083273 Open in new window
Abstract
The paper describes the use of frequentist and Bayesian shared-parameter joint models of longitudinal measurements of prostate specific antigen (PSA) and the risk of prostate cancer (PCa). The motivating dataset corresponds to the screening arm of the Spanish branch of the European Randomized Screening for Prostate Cancer (ERSPC) study. The results show that PSA is highly associated with the risk of being diagnosed with PCa and that there is an age-varying effect of PSA on PCa risk. Both the fr...
Citation
Serrat, C., Rué, M., Perpiñán, H., Forte, A., Armero, C., Piulachs, X., Páez, Á., Gomez, G. A shared-parameter joint model for prostate cancer risk and psa longitudinal profiles. A: International Conference on Risk Analysis. "Current topics on risk analysis: ICRA 6 and RISK 2015 conference". Barcelona: Fundación Mapfre, 2015, p. 711-719.
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Serrat Pie, Carles  (author and speaker )
  • Rué, Montserrat  (author and speaker )
  • Perpiñán Fabuel, Hèctor  (author and speaker )
  • Forte, Anabel  (author and speaker )
  • Armero, Carmen  (author and speaker )
  • Piulachs Lozada Benavente, Xavier  (author and speaker )
  • Páez, Álvaro  (author and speaker )
  • Gomez Melis, Guadalupe  (author and speaker )

Attachments