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The extracellular N-terminal domain suffices to discriminate class C G Protein-Coupled Receptor subtypes from n-grams of their sequences

Author
König, C.; Alquezar, R.; Vellido, A.; Giraldo, J.
Type of activity
Presentation of work at congresses
Name of edition
2015 International Joint Conference on Artificial Neural Networks
Date of publication
2015
Presentation's date
2015-07-14
Book of congress proceedings
2015 International Joint Conference on Neural Networks (IJCNN 2015): Killarney, Ireland, 12-17 July 2015
First page
1
Last page
7
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
DOI
https://doi.org/10.1109/IJCNN.2015.7280613 Open in new window
Repository
http://hdl.handle.net/2117/82851 Open in new window
URL
http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7280613 Open in new window
Abstract
The investigation of protein functionality often relies on the knowledge of crystal 3-D structure. This structure is not always known or easily unravelled, which is the case of eukaryotic cell membrane proteins such as G Protein-Coupled Receptors (GPCRs) and specially of those of class C, which are the target of the current study. In the absence of information about tertiary or quaternary structures, functionality can be investigated from the primary structure, that is, from the amino acid seque...
Citation
König, C., Alquézar, R., Vellido, A., Giraldo, J. The extracellular N-terminal domain suffices to discriminate class C G Protein-Coupled Receptor subtypes from n-grams of their sequences. A: International Joint Conference on Artificial Neural Networks. "2015 International Joint Conference on Neural Networks (IJCNN 2015): Killarney, Ireland, 12-17 July 2015". Killarney: Institute of Electrical and Electronics Engineers (IEEE), 2015, p. 1-7.
Keywords
Bioinformatics, Biomembranes, Cellular biophysics, Feature selection, Molecular biophysics, Molecular configurations, Pattern classification, Proteins
Group of research
IDEAI-UPC - Intelligent Data Science and Artificial Intelligence Research Center
SOCO - Soft Computing
VIS - Artificial Vision and Intelligent Systems

Participants

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