The main objective of the team is the study of biological macromolecules using crystallographic methods. Many synthetic oligonucleotide structures have been studied, which have provided information on new DNA forms (Hoogsteen, recombinants, superhelix, etc.). The team also studies the structure and function of several proteins and drugs, as well as their interactions with DNA. The proteins and their variants are prepared directly from the tissue or by expression in procariotes. Site-directed mutagenesis is also used.
Campos, J.Lourdes; De Luchi, D.; Sanmartin, T.; Urpí, L.; Subirana, J. XXVII Congreso de la Sociedad Española de Bioquímica y Biología Molecular p. 100 Presentation's date: 2004-09 Presentation of work at congresses
Lewis, J.; Saperas, N.; Song, Y.; Zamora, M.; Chiva, M.; Ausió, J. Proceedings of the National Academy of Sciences of the United States of America Vol. 101, num. 12, p. 4148-4152 Date of publication: 2004-03 Journal article
Campos, J.Lourdes; Urpí, L.; De Luchi, D.; Sanmartin, T.; Subirana, J. Reunion Nacional de Usuarios de Radiación Sincrotrón. Constitución de AUSE Presentation's date: 2004-02 Presentation of work at congresses
Soler, M.; Ortega, S.; Soriano, C.; Pino, D.; Alarcon, M.; Aymami, J. 9th International Conference on Harmonisation within Atmospheric Dispersion Modelling fir Regulatory Purposes p. 309-314 Presentation of work at congresses