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Calcium alternans is a global order-disorder phase transition. Robustness on Ryanodine Receptor release dynamics

Author
Alvarez-Lacalle, E.; Peñaranda, A.; Rodriguez Cantalapiedra, I.; Shiferaw, Y.; Echebarria, B.
Type of activity
Presentation of work at congresses
Name of edition
Computing in Cardiology 2015
Date of publication
2015
Presentation's date
2015-09-08
Book of congress proceedings
Computing in Cardiology 2015; 42
First page
329
Last page
332
DOI
https://doi.org/10.1109/CIC.2015.7408653 Open in new window
Repository
http://hdl.handle.net/2117/86185 Open in new window
http://www.cinc.org/archives/2015/pdf/0329.pdf Open in new window
Abstract
Electromechanical alternans is a beat-to-beat alterna- tion in the strength of contraction of a cardiac cell which appears often due to an instability of calcium cycling. The global calcium signal in cardiomyocytes is the result of the combined effect of several thousand micron scale domains called Calcium Release Units (CaRU), coupled through diffusion, where the flow of calcium among different cell compartments is regulated by stochastic signaling involv- ing the ryanodine receptor (RyR)...
Citation
Alvarez-Lacalle, E., Peñaranda, A., Rodriguez Cantalapiedra, I., Shiferaw, Y., Echebarria, B. Calcium alternans is a global order-disorder phase transition. Robustness on Ryanodine Receptor release dynamics. A: Computing in Cardiology Annual Conference. "Computing in Cardiology 2015; 42". Nice: 2015, p. 329-332.
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

Participants

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