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MMPs/TIMPs and inflammatory signalling de-regulation in human incisional hernia tissues

Author
Guillem-Marti, J.; Diaz, R.; Quiles, M.T.; López , M.; Vilallonga, R.; Huguet, P.; Ramon-y-Cajal, S.; Sánchez-Niubó, A.; Armengol, M.; Reventós, J.; Arbós, M.A.
Type of activity
Journal article
Journal
Journal of cellular and molecular medicine
Date of publication
2009-11-01
Volume
13
Number
11-12
First page
4432
Last page
4443
DOI
https://doi.org/10.1111/j.1582-4934.2008.00637.x Open in new window
Repository
http://hdl.handle.net/2117/86556 Open in new window
URL
http://onlinelibrary.wiley.com/doi/10.1111/j.1582-4934.2008.00637.x/full Open in new window
Abstract
Incisional hernia is a common and important complication of laparotomies. Epidemiological studies allude to an underlying biological cause, at least in a subset of population. Interest has mainly focused on abnormal collagen metabolism. However, the role played by other determinants of extracellular matrix (ECM) composition is unknown. To date, there are few laboratory studies investigating the importance of biological factors contributing to incisional hernia development. We performed a descrip...
Citation
Guillem-Marti, J., Diaz, R., Quiles, M.T., López-Cano, M., Vilallonga, R., Huguet, P., Ramon-y-Cajal, S., Sanchez-Niubo, A., Armengol, M., Reventós, J., Arbós, M.A. MMPs/TIMPs and inflammatory signalling de-regulation in human incisional hernia tissues. "Journal of cellular and molecular medicine", 01 Novembre 2009, vol. 13, núm. 11-12, p. 4432-4443.
Keywords
IL-6, Incisional hernia, MMP/TIMP, TNFA, TNFRSFs, aponeurosis, extracellular matrix, skeletal muscle
Group of research
BBT - Biomaterials, Biomechanics and Tissue Engineering
CRnE - Barcelona Research Center in Multiscale Science and Engineering

Participants

  • Guillem Marti, Jordi  (author)
  • Diaz, Ramon  (author)
  • Quiles Pérez, María Teresa  (author)
  • López Cano, Manuel  (author)
  • Vilallonga, Ramon  (author)
  • Huguet, Pere  (author)
  • Ramon-y-Cajal, Santiago  (author)
  • Sánchez Niubó, Albert  (author)
  • Armengol, Manel  (author)
  • Reventós, Jaume  (author)
  • Arbós Vilà, Maria Antonia  (author)