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Complex physical and biophysical systems: towards a comprehensive view of their dynamics and fluctuations

Total activity: 17
Type of activity
Competitive project
Funding entity
MIN DE ECONOMIA Y COMPETITIVIDAD
Acronym
ComPhysBio
Funding entity code
FIS2015-66503-C3-2-P
Amount
88.935,00 €
Start date
2016-01-01
End date
2018-12-31
Keywords
biología de sistemas, complex systems, dinámica no lineal, física estadística, neurodinámica, neurodynamics, noise, nonlinear dynamics, nonlinear optics, ruido, sistemas complejos, statistical physics, systems biology, óptica no lineal
Abstract
During the past decades, theoretical advances in nonequilibrium statistical mechanics and nonlinear physics are allowing us to develop a
powerful conceptual framework within which to understand the behavior of complex systems from first principles. More recently,
unprecedented breakthroughs in our ability to measure and control experimentally these systems have finally put us in a position that
should enable the validation of this conceptual framework. Current technical innovations in fields ranging from photonics to molecular
biology and neuroscience offer now the possibility of generating large amounts of experimental information in highly controlled conditions.
The aim of this coordinated project is to exploit a long and fruitful collaborative programme between the participating teams, which has
been in place for more than two decades and which will now lead, via an extensive use of quantitative experimental data generated by us
and by external collaborators, to a qualitative shift in our understanding of the dynamic and stochastic behavior of a variety of physical and
biophysical systems. The phenomena to be studied include Brownian motion of colloidal particles, the dynamics of complex fluids, laserinduced
fracture, information processing by optical networks, extreme events in complex systems, transcriptional regulation, gene circuit
dynamics and variability, pattern formation in cellular populations, cellular decision making, biochemical signaling of the immune response,
the dynamical rhythms of the gut microbiome, self-organization in bacterial biofilms, neural excitability, and brain dynamics, among others.
The many synergies between the three teams of our coordinated project, resulting from a long history of joint work and from the use of
common techniques coming from statistical and nonlinear physics, will enable a cross-fertilization between the different topics under study,
and bring us closer to reaching a comprehensive view of the dynamics and fluctuations of complex physical and biophysical systems.
Scope
Adm. Estat
Plan
Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016
Call year
2016
Funcding program
Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia
Funding subprogram
Subprograma Estatal de Generación de Conocimiento
Funding call
Excelencia: Proyectos I+D
Grant institution
Gobierno De España. Ministerio De Economía Y Competitividad, Mineco

Scientific and technological production

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