Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Design of calcium phosphate scaffolds with controlled simvastatin release by plasma polymerisation

Autor
Canal, C.; Khurana, K.; Gallinetti, S.; Bhatt, S.; Pulpytel, J.; Arefi, F.; Ginebra, M.P.
Tipus d'activitat
Article en revista
Revista
Polymer
Data de publicació
2016-06-01
Volum
92
Pàgina inicial
170
Pàgina final
178
DOI
https://doi.org/10.1016/j.polymer.2016.03.069 Obrir en finestra nova
Projecte finançador
Nuevas estrategias de bioimpresión para regeneración osea y terapias anticáncer
Repositori
http://hdl.handle.net/2117/89972 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0032386116302166 Obrir en finestra nova
Resum
Calcium Phosphates (CaPs) have excellent bone regeneration capacity, and their combination with specific drugs is of interest because it allows adding new functionalities. In CaPs, drug release is mainly driven by diffusion, which is strongly affected by the porosity of the matrix and the drug-material interaction. Therefore, it is very difficult to tune their drug release properties beyond their intrinsic properties. Furthermore, when the CaPs are designed as scaffolds, the increased complexity...
Citació
Canal, C., Khurana, K., Gallinetti, S., Bhatt, S., Pulpytel, J., Arefi, F., Ginebra, M.P. Design of calcium phosphate scaffolds with controlled simvastatin release by plasma polymerisation. "Polymer", 1 Juny 2016, vol. 92, p. 170-178.
Paraules clau
Calcium phosphate, Cements, Ceramics, Controlled drug release, PCL-PEG plasma polymerisation, Scaffolds, behavior, cements, drug-delivery, in-vitro, polypropylene, statins
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants

Arxius