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Electromechanical conditioning of adult progenitor cells improves recovery of cardiac function after myocardial infarction

Author
Llucía, A.; Soler, C.; Gálvez, C.; Roura, S.; Cristina Prat-Vidal; Perea, I.; Sánchez, B.; Bragos, R.; Vunjak-Novakovic, G.; Bayés-Genis, A.
Type of activity
Journal article
Journal
Stem cells translational medicine
Date of publication
2016-09-29
Volume
6
Number
5
First page
970
Last page
981
DOI
https://doi.org/10.5966/sctm.2016-0079 Open in new window
Repository
http://hdl.handle.net/2117/104365 Open in new window
URL
http://stemcellstm.alphamedpress.org/content/early/2016/09/29/sctm.2016-0079.abstract Open in new window
Abstract
Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. Our goals were (a) to study the viability of a tissue engineered construct with cardiac adipose tissue-derived progenitor cells (cardiac ATDPCs) and (b) to examine the effect of electromechanically stimulated cardiac ATDPCs within a myocardial infarction (MI)...
Citation
Llucia, A., Soler, C., Gálvez, C., Roura, S., Cristina Prat-Vidal, Perea, I., Sánchez, B., Bragos, R., Vunjak-Novakovic, G., Bayés-Genis, A. Electromechanical conditioning of adult progenitor cells improves recovery of cardiac function after myocardial infarction. "Stem Cells Translational Medicine", 29 Setembre 2016, vol. 6, núm. 5, p. 970-981.
Keywords
Biomedical Engineering, Cardiac regeneration, Electromechanical conditioning, Myocardial infarction, Tissue engineering
Group of research
CREB - Biomedical Engineering Research Centre
IEB - Electronic and Biomedical Instrumentation

Participants

  • Llucía Valldeperas, Aida  (author)
  • Soler Botija, Carolina  (author)
  • Gálvez Montón, Carolina  (author)
  • Roura Ferrer, Santiago  (author)
  • Prat Vidal, Cristina  (author)
  • Perea Gil, Isaac  (author)
  • Sánchez Terrones, Benjamin  (author)
  • Bragos Bardia, Ramon  (author)
  • Vunjak-Novakovic, Gordana  (author)
  • Bayés Genis, Antoni  (author)