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Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans

Autor
Valle, M.; Maqueda, A.; Rabella, M.; Rodríguez, A.; Antonijoan, R. M.; Romero, S.; Alonso, J.F.; Mañanas, M.A.; Barker, S.; Friedlander, P.; Feilding, A.; Riba, J.
Tipus d'activitat
Article en revista
Revista
European neuropsychopharmacology
Data de publicació
2016-07
Volum
26
Número
7
Pàgina inicial
1161
Pàgina final
1175
DOI
https://doi.org/10.1016/j.euroneuro.2016.03.012 Obrir en finestra nova
Projecte finançador
Diseño de métodos para la evaluación de procesos de deterioro neurológico y neuromuscular asociados al envejecimiento (ref. DPI2014-59049-R)
Repositori
http://hdl.handle.net/2117/101863 Obrir en finestra nova
URL
http://www.europeanneuropsychopharmacology.com/article/S0924-977X(16)30010-4/abstract Obrir en finestra nova
Resum
Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic 5-HT2A and sigma-1 agonist N,N-dimethyltryptamine (DMT) plus ß-carboline alkaloids with monoamine-oxidase (MAO)-inhibiting properties. Although the psychoactive effects of ayahuasca have commonly been attributed solely to agonism at the 5-HT2A receptor, the molecular target of classical psychedelics, this has not been tested experimentally...
Citació
Valle, M., Ana Elda, M., Rabella, M., Rodríguez, A., Antonijoan, R. M., Romero, S., Alonso, J.F., Mañanas, M.A., Barker, S., Friedlander, P., Feilding, A., Riba, J. Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans. "European neuropsychopharmacology", Juliol 2016, vol. 26, núm. 7, p. 1161-1175.
Paraules clau
Human, Ketanserin, Neurophysiological effects, Serotonin-2A receptor, Subjective effects
Grup de recerca
BIOART - BIOsignal Analysis for Rehabilitation and Therapy
CREB - Centre de Recerca en Enginyeria Biomedica

Participants

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