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Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria

Autor
Fernandes, M.; Ivanova, K.; Hoyo, J.; Perez, S.; Francesko, A.; Tzanov, T.
Tipus d'activitat
Article en revista
Revista
ACS applied materials and interfaces
Data de publicació
2017-04-10
Volum
9
Número
17
Pàgina inicial
15022
Pàgina final
15030
DOI
https://doi.org/10.1021/acsami.7b00217 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/103542 Obrir en finestra nova
URL
http://pubs.acs.org/doi/abs/10.1021/acsami.7b00217 Obrir en finestra nova
Resum
The increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of multidrug- resistant species. In this study, we developed a novel broad-spectrum antimicrobial agent by simply transforming vancomycin into nanoform using sonochemistry. Vancomycin is a glycopeptide antibiotic largely used for the treatment of infections caused by Gram-positive ba...
Citació
Fernandes, M.M., Ivanova, K., Hoyo, J., Perez-Rafael, S., Francesko, A., Tzanov, T. Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria. "ACS applied materials and interfaces", 10 Abril 2017.
Paraules clau
Vancomycin, antibiotic nanospheres, antibiotic resistance, biofilms, sonochemistry
Grup de recerca
GBMI - Grup de Biotecnologia Molecular i Industrial

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