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Multifunctional enzymatically generated hydrogels for chronic wound application

Author
Stefanov, I.; Perez, S.; Hoyo, J.; Cailloux, J.; Santana, O.; Hinojosa, D.; Tzanov, T.
Type of activity
Journal article
Journal
Biomacromolecules
Date of publication
2017-04-19
Volume
18
Number
5
First page
1544
Last page
1555
DOI
https://doi.org/10.1021/acs.biomac.7b00111 Open in new window
Repository
http://hdl.handle.net/2117/103739 Open in new window
URL
http://pubs.acs.org/doi/abs/10.1021/acs.biomac.7b00111 Open in new window
Abstract
The healing of chronic wounds requires intensive medical intervention at huge healthcare costs. Dressing materials should consider the multifactorial nature of these wounds comprising deleterious proteolytic and oxidative enzymes and high bacterial load. In this work, multifunctional hydrogels for chronic wound application were produced by enzymatic cross- linking of thiolated chitosan and gallic acid. The hydrogels combine several beneficial to wound healing properties, controlling the matrix m...
Citation
Stefanov, I., Perez-Rafel, S., Hoyo, J., Cailloux, J., Santana, O., hinojosa-Caballero, D., Tzanov, T. Multifunctional enzymatically generated hydrogels for chronic wound application. "Biomacromolecules", 19 Abril 2017.
Group of research
GBMI - Molecular and Industrial Biotechnology Group
e-PLASCOM - Eco-friendly Plastics and Composites

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