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Variable endothelial cell function restoration after initiation of two antiretroviral regimens in HIV-infected individuals

Author
Echevarría, P.; Gómez, E.; Roura, S.; Bonjoch, A.; Puig, J.; Perez, N.; Bayés-Genis, A.; Clotet, B.; Blanco, J.; Negredo, E.
Type of activity
Journal article
Journal
Journal of antimicrobial chemotherapy
Date of publication
2017-07-01
Volume
72
Number
7
First page
2049
Last page
2054
DOI
https://doi.org/10.1093/jac/dkx074 Open in new window
URL
https://academic.oup.com/jac/article-abstract/72/7/2049/3077301/Variable-endothelial-cell-function-restoration?redirectedFrom=fulltext Open in new window
Abstract
Background: The effect of ART on endothelial cell function is incompletely characterized. Methods: We performed a 24 week prospective, case–control and comparative pilot study of ART-naive HIV-infected patients who started a darunavir- or rilpivirine-based regimen, matched with non-HIV-infected volunteers, to compare changes at week 24 from baseline in levels of circulating endothelial cells (CECs), endothelial progenitor cells (EPCs) and circulating angiogenic cells, as well as changes in imm...
Keywords
angiogenesis, anti-retroviral agents, chronic exertional compartment syndrome, darunavir, endothelial cells, endothelial progenitor cells, endothelium, hiv, hiv infection, rilpivirine, t-lymphocyte, viremia
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Echevarría, Patricia  (author)
  • Gómez Mora, E.  (author)
  • Roura Ferrer, Santiago  (author)
  • Bonjoch Badia, Anna  (author)
  • Puig Domingo, Jordi  (author)
  • Perez Alvarez, Nuria  (author)
  • Bayés Genis, Antoni  (author)
  • Clotet Sala, Bonaventura  (author)
  • Blanco, Julia  (author)
  • Negredo Puigmal, Eugènia  (author)