Loading...
Loading...

Go to the content (press return)

Genuine antiplasticizing effect of water on a glass-former drug

Author
Ruiz, G.; Romanini, M.; Hauptmann, A.; Loerting, T.; Shalaev, E.; Tamarit, J. Ll.; Pardo, L.; Macovez, R.
Type of activity
Journal article
Journal
Scientific reports
Date of publication
2017-08-07
Volume
7
First page
1
Last page
8
DOI
https://doi.org/10.1038/s41598-017-07643-5 Open in new window
Project funding
Organic and metallic glasses: structure, dynamics and stability
Repository
http://hdl.handle.net/2117/108032 Open in new window
URL
https://www.nature.com/articles/s41598-017-07643-5 Open in new window
Abstract
Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass transition temperature (T g ), is considered a universal result of hydration. In fact, even in the cases where hydration or humidification of an organic glass-forming sample result in stiffer mechanic...
Citation
Ruiz, G., Romanini, M., Hauptmann, A., Loerting, T., Shalaev, E., Tamarit, J. Ll., Pardo, L., Macovez, R. Genuine antiplasticizing effect of water on a glass-former drug. "Scientific reports", 7 Agost 2017, vol. 7, p. 1-8.
Group of research
CRnE - Barcelona Research Center in Multiscale Science and Engineering
GCM - Group of Characterization of Materials

Participants

Attachments