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Effect of solvent choice on the self-assembly properties of a diphenylalanine amphiphile stabilized by an ion pair

Author
Mayans, E.; Ballano, G.; Sendros, J.; Font-Bardia, M.; Campos, J.Lourdes; Puiggali, J.; Cativiela, C.; Aleman, C.
Type of activity
Journal article
Journal
Chemphyschem
Date of publication
2017-07-19
Volume
18
Number
14
First page
1888
Last page
1896
DOI
https://doi.org/10.1002/cphc.201700180 Open in new window
Repository
http://hdl.handle.net/2117/109766 Open in new window
URL
http://onlinelibrary.wiley.com/doi/10.1002/cphc.201700180/abstract Open in new window
Abstract
A diphenylalanine (FF) amphiphile blocked at the C terminus with a benzyl ester (OBzl) and stabilized at the N terminus with a trifluoroacetate (TFA) anion was synthetized and characterized. Aggregation of peptide molecules was studied by considering a peptide solution in an organic solvent and adding pure water, a KCl solution, or another organic solvent as co-solvent. The choice of the organic solvent and co-solvent and the solvent/co-solvent ratio allowed the mixture to be tuned by modulating...
Citation
Mayans, E., Ballano, G., Sendros, J., Font-Bardia, M., Campos, J.Lourdes, Puiggali, J., Cativiela, C., Aleman, C. Effect of solvent choice on the self-assembly properties of a diphenylalanine amphiphile stabilized by an ion pair. "Chemphyschem", 19 Juliol 2017, vol. 18, núm. 14, p. 1888-1896.
Keywords
fibers, hydrophilic core, nanostructures, peptide materials, stacking interactions
Group of research
CEBIM - Molecular Biotechnology Centre
CRnE - Barcelona Research Center in Multiscale Science and Engineering
IMEM-BRT - Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
MACROM - Crystallography, Structure and Function of Biological Macromolecules
PSEP - Synthetic Polymers: Structure and Properties. Biodegradable Polymers.

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