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Automatic segmentation of Z-lines in cardiac cells from microscope fluorescence images

Autor
Nolla-Colomer, C.; Vallmitjana, A.; Marchena, M.; Echebarria, B.; Herraiz, A.; Hove-Madsen, L.; Wayne Chen, S. R.; Benitez, R.
Tipus d'activitat
Presentació treball a congrés
Nom de l'edició
39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Any de l'edició
2017
Data de presentació
2017-04-14
Llibre d'actes
EMBC'17: 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: July 11-15, 2017: International Convention Center (ICC), Jeju Island, Korea
Resum
We present an approach to quantify the spatial distribution of ryanodine receptors based on regional maxima segmentation and Z-lines segmentation using FFT and posterior clustering in mouse ventricular myocytes. The method provides an excellent performance under different settings, such as synthetic cell models and experimental conditions.
Grup de recerca
ANCORA - Anàlisi i control del ritme cardíac
B2SLab - Bioinformatics and Biomedical Signals Laboratory
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos
CREB - Centre de Recerca en Enginyeria Biomedica

Participants