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Excessive activation of beta-2 adrenergic receptors induces arrhythmic calcium oscillations and ryanodine receptor phosphorylation at ser2809 but not at ser2815

Jiménez-Sábado, V.; Nolla-Colomer, C.; Chun, G.; Sheng, H.; Tarifa, C.; Herraiz, A.; Vallmitjana, A.; Wayne Chen, S. R.; Benitez, R.; Tibbits, G.; Hove-Madsen, L.
Type of activity
Presentation of work at congresses
Name of edition
European Society of Cardiology Congress 2017
Date of publication
Presentation's date
Book of congress proceedings
European Heart Journal. ESC Congress 2017 26-30 August. Barcelona, Spain. Special edition. Volume 38, Suppl. 1 26 August 2017
First page
Last page
https://doi.org/10.1093/eurheartj/ehx504.P3999 Open in new window
https://academic.oup.com/eurheartj/article/38/suppl_1/ehx504.P3999/4090241/P3999Excessive-activation-of-beta-2-adrenergic Open in new window
Our findings suggest that prevention of PKA-dependent phosphorylation of the RyR2 at ser2809 may be a means to prevent arrhythmic calcium release induced by excessive beta-2 adrenergic stimulation.
Group of research
ANCORA - Anàlisi i control del ritme cardíac
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Biomedical Engineering Research Centre


  • Jiménez Sábado, Verónica  (author and speaker )
  • Nolla Colomer, Carme  (author and speaker )
  • Chun, Grace  (author and speaker )
  • Sheng, Helen  (author and speaker )
  • Tarifa Lora, Carmen  (author and speaker )
  • Herraiz Martínez, Adela  (author and speaker )
  • Vallmitjana Lees, Alexander  (author and speaker )
  • Chen, S. R. Wayne  (author and speaker )
  • Benitez Iglesias, Raul  (author and speaker )
  • Tibbits, Glen  (author and speaker )
  • Hove-Madsen, Leif  (author and speaker )