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Spatial localization of ryanodine receptors in human cardiac cells

Autor
Vallmitjana, A.; Nolla-Colomer, C.; Herraiz, A.; Hove-Madsen, L.; Benitez, R.
Tipus d'activitat
Presentació treball a congrés
Nom de l'edició
37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Any de l'edició
2015
Data de presentació
2015-04-14
Llibre d'actes
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2015): Milan, Italy: 25-29 August 2015
Pàgina inicial
6297
Pàgina final
6300
DOI
https://doi.org/10.1109/EMBC.2015.7319832 Obrir en finestra nova
URL
http://ieeexplore.ieee.org/document/7319832/ Obrir en finestra nova
Resum
We present a novel image processing method to determine the location of ryanodine receptors in cardiac cells. A semi-automatic manual validation by an expert has been used in order to establish the performance of the segmentation method. The approach provides high accuracy under different experimental conditions and it is robust to common sources of noise including experimental, molecular and biological fluctuations.
Paraules clau
Biomedical monitoring, Biomembranes, Calcium, Detection algorithms, Fluorescence, Labeling, Robustness
Grup de recerca
ANCORA - Anàlisi i control del ritme cardíac
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Centre de Recerca en Enginyeria Biomedica

Participants