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Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B

Author
Rosas, M.; Mothe, B.; Noguera, M.; Bellido, R.; Puertas, M.; Carrillo, J.; Rodriguez, C.; Perez, N.; Corbasí, P.; Gomez, C.; Esteban, M.; Jímenez, J.; Botaya García, Felipe; Blanco, J.; Martínez, J.; Paredes Deirós, Roger; Brander, C.
Type of activity
Journal article
Journal
PloS one
Date of publication
2017-09-27
Volume
12
Number
9
First page
1
Last page
15
DOI
https://doi.org/10.1371/journal.pone.0184929 Open in new window
URL
http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184929&type=printable Open in new window
Abstract
The most relevant endpoint in therapeutic HIV vaccination is the assessment of time to viral rebound or duration of sustained control of low-level viremia upon cART treatment cessation. Structured treatment interruptions (STI) are however not without risk to the patient and reliable predictors of viral rebound/control after therapeutic HIV-1 vaccination are urgently needed to ensure patient safety and guide therapeutic vaccine development. Here, we integrated immunological and virological parame...
Group of research
GRBIO - Biostatistics and Bioinformatics Research Group

Participants

  • Rosas Umbert, Miriam  (author)
  • Mothe, Beatriz  (author)
  • Noguera Julian, Marc  (author)
  • Bellido, Rocio  (author)
  • Puertas Castro, Maria C.  (author)
  • Carrillo, Jorge  (author)
  • Rodriguez, C.  (author)
  • Perez Alvarez, Nuria  (author)
  • Corbasí, Patricia  (author)
  • Gomez, Carmen E.  (author)
  • Esteban, Mariano  (author)
  • Jímenez, Jose Luis  (author)
  • Botaya García, Felipe  (author)
  • Blanco, Julia  (author)
  • Martínez Picado, Javier  (author)
  • Paredes Deirós, Roger  (author)
  • Brander, Christian  (author)