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From genes to ecosystems in microbiology: modeling approaches and the importance of individuality

Author
Kreft, J.U.; Plugge, C.M.; Prats, C.; Leveau, J.H.J.; Zhang, W.; Hellweger, F.L.
Type of activity
Journal article
Journal
Frontiers in Microbiology
Date of publication
2017-11-27
Volume
8
First page
1
Last page
23
DOI
https://doi.org/10.3389/fmicb.2017.02299 Open in new window
Repository
http://hdl.handle.net/2117/113503 Open in new window
https://www.frontiersin.org/articles/10.3389/fmicb.2017.02299/full Open in new window
Abstract
Models are important tools in microbial ecology. They can be used to advance understanding by helping to interpret observations and test hypotheses, and to predict the effects of ecosystem management actions or a different climate. Over the past decades, biological knowledge and ecosystem observations have advanced to the molecular and in particular gene level. However, microbial ecology models have changed less and a current challenge is to make them utilize the knowledge and observations at th...
Citation
Kreft, J.U., Plugge, C.M., Prats, C., Leveau, J.H.J., Zhang, W., Hellweger, F.L. From genes to ecosystems in microbiology: modeling approaches and the importance of individuality. "Frontiers in Microbiology", 27 Novembre 2017, vol. 8, p. 1-23.
Keywords
agent-based modeling, gene-centric modeling, heterogeneity, individuality, metabolic flux modeling, microbial ecology, single cell.
Group of research
BIOCOM-SC - Computational Biology and Complex Systems Group

Participants

  • Kreft, Jan-Ulrich  (author)
  • Plugge, Caroline M.  (author)
  • Prats Soler, Clara  (author)
  • Leveau, Johan H. J.  (author)
  • Zhang, Weiwen  (author)
  • Hellweger, Ferdi L.  (author)

Attachments