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Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue

Author
Hawks, C.; Elorza, J.; Echebarria, B.; Rodriguez Cantalapiedra, I.; Peñaranda, A.; Bragard, J.
Type of activity
Journal article
Journal
Computing in Cardiology
Date of publication
2016-01-01
Volume
42
First page
437
Last page
440
Repository
http://hdl.handle.net/2117/113755 Open in new window
URL
http://www.cinc.org/archives/2015/pdf/0437.pdf Open in new window
Abstract
Constant conductances are often assumed when model- ing cardiac tissue. However experimental evidences have shown that gap junctions (GJ) actually connect adjacent cardiac myocytes. These GJ are complex proteins of the connexin family (Cx40; Cx43; Cx45 are the most common in human). These GJ modify the conductances between cardiac cell through a dynamical process. The aim of this study is to develop a bidomain model of the cardiac tis- sue where the dynamics of the connexins is also included. In...
Citation
Hawks, C., Elorza, J., Echebarria, B., Rodriguez Cantalapiedra, I., Peñaranda, A., Bragard, J. Influence of gap junction dynamics on the stability of reentrant waves in cardiac tissue. A: "Computers in Cardiology". 2016, p. 437-440.
Keywords
Cardiac Tissue, Gap junction dynamics, Reentrant Waves
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

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