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Minimal model for calcium alternans due to calcium release refractorinness

Author
Echebarria, B.; Rodriguez Cantalapiedra, I.; Alvarez-Lacalle, E.; Peñaranda, A.
Type of activity
Presentation of work at congresses
Name of edition
9th International Conference Engineering of Chemical Complexity
Date of publication
2017
Presentation's date
2017-06-22
Book of congress proceedings
9th International Conference Engineering of Chemical Complexity: ECC9 : book of abstracts
First page
56
Last page
56
Abstract
Cardiac excitation starts at the sino atrial node as a periodic change in the myocytes’ transmembrane potential that then propagates along the atria and ventricles, inducing the contraction of the heart and the pumping of blood throughout the body. Rapid pacing rates may induce alternations in the strength of cardiac contraction, termed pulsus alternans. Often, this is due to an instability in the dynamics of intracellular calcium concentration such that it becomes larger and smaller at consec...
Group of research
ANCORA - Anàlisi i control del ritme cardíac
BIOCOM-SC - Computational Biology and Complex Systems Group
GICITED - Interdisciplinary Group on Building Scienceand and Technology

Participants