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Thermomechanical response of a representative porin for biomimetics

Author
Lopes, M.; Puiggali, A.; Martí, D.; del Valle, LJ.; Michaux, Catherine Anne Gisèle; Perpète, Eric A.; Aleman, C.
Type of activity
Journal article
Journal
ACS omega
Date of publication
2018-07-31
Volume
3
Number
7
First page
7856
Last page
7867
DOI
https://doi.org/10.1021/acsomega.8b00463 Open in new window
Repository
http://hdl.handle.net/2117/130343 Open in new window
URL
https://pubs.acs.org/doi/10.1021/acsomega.8b00463# Open in new window
Abstract
The thermomechanical response of Omp2a, a representative porin used for the fabrication of smart biomimetic nanomembranes, has been characterized using microcantilever technology and compared with standard proteins. For this purpose, thermally induced transitions involving the conversion of stable trimers to bigger aggregates, local reorganizations based on the strengthening or weakening of intermolecular interactions, and protein denaturation have been detected by the microcantilever resonance ...
Citation
Lopes, M. [et al.]. Thermomechanical response of a representative porin for biomimetics. "ACS omega", 31 Juliol 2018, vol. 3, núm. 7, p. 7856-7867.
Keywords
Albumins, Mechanical properties, Molecular dynamics, Proteins, Thermal properties
Group of research
CRnE - Barcelona Research Center in Multiscale Science and Engineering
IMEM-BRT - Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Synthetic Polymers: Structure and Properties. Biodegradable Polymers

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