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Effect of nano-structural properties of biomimetic hydroxyapatite on osteoimmunomodulation

Autor
Sadowska, J.; Wei, F.; Guo, J.; Guillem-Marti, J.; Ginebra, M.P.; Xiao, Y.
Tipus d'activitat
Article en revista
Revista
Biomaterials
Data de publicació
2018-10
Volum
181
Pàgina inicial
318
Pàgina final
332
DOI
https://doi.org/10.1016/j.biomaterials.2018.07.058 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/121915 Obrir en finestra nova
https://www.sciencedirect.com/science/article/pii/S0142961218305490 Obrir en finestra nova
Resum
Immune cells are sensitive to the microstructural and textural properties of materials. Tuning the structural features of synthetic bone grafts could be a valuable strategy to regulate the specific response of the immune system, which in turn modulates the activity of bone cells. The aim of this study was to analyse the effect of the structural characteristics of biomimetic calcium deficient hydroxyapatite (CDHA) on the innate immune response of macrophages and the subsequent impact on osteogene...
Citació
Sadowska, J., Wei, F., Guo, J., Guillem-Marti, J., Ginebra, M.P., Xiao, Y. Effect of nano-structural properties of biomimetic hydroxyapatite on osteoimmunomodulation. "Biomaterials", Octubre 2018, vol. 181, p. 318-332.
Paraules clau
Calcium phosphates Biomimetic hydroxyapatite Osteoimmunomodulation Inflammation Osteogenesis Osteoclastogesis
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants

Arxius