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Model-based analysis of the autonomic response to head-up tilt testing in Brugada syndrome

Autor
Calvo, M.; Le Rolle, V.; Romero, D.; Gomis, P.; Hernández, A.
Tipus d'activitat
Article en revista
Revista
Computers in biology and medicine
Data de publicació
2018-12-01
Volum
103
Pàgina inicial
82
Pàgina final
92
DOI
https://doi.org/10.1016/j.compbiomed.2018.10.007 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/125275 Obrir en finestra nova
URL
https://www.sciencedirect.com/science/article/pii/S0010482518303007 Obrir en finestra nova
Resum
The etiology of Brugada syndrome (BS) is complex and multifactorial, making risk stratification in this population a major challenge. Since changes in the autonomic modulation of these patients are commonly related to arrhythmic events, we analyze in this work whether the response to head-up tilt (HUT) testing on this population may provide useful, complementary information for risk stratification. In order to perform this analysis, a coupled physiological model integrating the cardiac electrica...
Paraules clau
Autonomic nervous system Brugada syndrome Physiological model Sensitivity analysis Parameter identification
Grup de recerca
B2SLab - Bioinformatics and Biomedical Signals Laboratory
CREB - Centre de Recerca en Enginyeria Biomedica

Participants

  • Calvo, Mireia  (autor)
  • Le Rolle, Virginie  (autor)
  • Romero, Daniel  (autor)
  • Gomis Román, Pedro  (autor)
  • Hernández, Alfredo I.  (autor)